Malarial Facts



Do you know that?

Pregnant women especially those pregnant for the first time are up to 10 times more likely to contract and develop severe malaria than women that have never been pregnant. Centre for Disease Control advises pregnant women and women likely to get pregnant to stay away from malaria-endemic areas.

Female anopheles mosquitoes transmit malaria not males. Mammalian blood is nourishing to their developing eggs. Males feed on nectar.

Male anopheles mosquito feed during the day and females feed at night.

Renal problems and pulmonary edema(fluid accumulation in the lungs) are complications that can arise from P falciparum infection.

Malaria could cause a heart attack. P falciparum could obstruct blood vessels due to its ability to adhere to endothelial cell walls.

Red meat and pork may antagonise the effect of ACTs treatment, they have high iron content.

Guava and oranges contain vitamin C which inhibits the activity of ACTs in malarial treatment.

People with sickle cell traits are protected from malaria. Sickle cell erythrocytes produce higher levels of free radicals than normal erythrocytes that could be destructive to P falciparum.

Blood transfusions and use of infected needles are other modes of transmission for malaria.

P falciparum is becoming resistant to artemisinin- the active drug against malaria. Where do we go from here?

Deficiency of G6PD (an enzyme relevant in pentose phosphate pathway) predisposes patients to haemolysis; red blood cells are destroyed immediately they get matured due to oxidative stress. P falciparum infects only matured red blood cells. Deficiency of G6PD makes red blood cells unavailable for malaria parasite.
RAVIMAL stops malaria. Full stop.

Compiled by Ifeyinwa Ugo-Amadi





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